Metabolic restoration in HIV-infected patients as a therapeutic approach

Metabolic restoration in HIV-infected patients as a therapeutic approach

Metabolic restoration in HIV-infected patients as a therapeutic approach The human immunodeficiency virus (HIV-1) particularly attacks CD4 lymphocytes, a type of white blood cell considered to be the conductor of the immune system. Hamza Loucif, a doctoral student in virology and immunology, and Julien van Grevenynghe, a professor at the Institut national de la recherche scientifique (INRS), have shown that optimizing the energy metabolism of these key cells enables people with HIV-1 to better defend themselves against the virus. Indeed, with better metabolism, the role of these white blood cells in protecting against the virus, and thus in improving the overall immune system response, becomes more important. A combined action This metabolic optimization exploits the cell recycling process, called "autophagy." It would have a positive double effect! Autophagy in CD4 …
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