Increased transmission in open spike conformations of SARS-CoV-2 variants

Increased transmission in open spike conformations of SARS-CoV-2 variants

The initial strain severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was found in Wuhan, in China. Due to high transmission rates, the virus rapidly spread around the world. Over 4.87 million people have died so far, and many countries have been plunged into economic crises due to the harsh restrictions required to prevent the further spread of the disease. These included social distancing measures, face masks, and in many countries, complete lockdowns. Study: SARS-CoV-2 variants exhibit increased kinetic stability of open spike conformations as an evolutionary strategy. Image Credit: Adao/ Shutterstock Mass vaccination schemes are beginning to allow some of these restrictions to be removed, but concerns remain over dangerous variants of concern (VOCs) that are becoming more prevalent. One of the most worrying strains is the Delta variant - …
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