Asymptomatic SARS-CoV-2 individuals with blood group AB at highest risk

Asymptomatic SARS-CoV-2 individuals with blood group AB at highest risk

The COVID-19 pandemic has resulted in several waves of infection in many countries worldwide. The significant variations in case fatality ratio among different geographical regions suggest that the human susceptibility against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) varies substantially. Scientists worldwide are conducting extensive research to understand the nature of the virus, its transmission kinetics, etc. They have found a strong correlation between the ABO blood group and SARS-CoV-2 regarding its morbidity and mortality. Previous studies have shown the relationship between the ABO blood group and several viral diseases. Researchers have reported that among the people inhabiting the Indian Gangetic plain, individuals with the blood group O are most vulnerable to cholera and Helicobacter pylori infection. Nevertheless, this blood group was reported to be less susceptible to dengue and SARS (Severe Acute Respiratory Syndrome) viruses. The ABO blood type is determined by the gene ABO, present at chromosome 9. Several pieces of research have indicated that this gene directly or indirectly moderates an individual's COVID-19 susceptibility. Further research reported that some of the variants of this gene might play an …
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